[7] Cancun FC 1-0 Tlaxcala FC [11] 2022-04-07 02:05
Stadium: Estadio Olimpico Andres Quintana Roo Round: 16
Head to Head
| Mexico Liga de Expansion | 2021/11/02 23:00 | Tlaxcala FC v Cancun FC | L | 3-1 |
| Mexico Liga de Expansion | 2021/03/31 23:00 | Tlaxcala FC v Cancun FC | L | 1-0 |
| Mexico Liga de Expansion | 2020/11/26 23:00 | Cancun FC v Tlaxcala FC | L | 1-2 |
| Mexico Liga de Expansion | 2020/11/02 01:30 | Cancun FC v Tlaxcala FC | W | 2-0 |