[12] San Lorenzo 0-1 River Plate [4] 2022-03-05 20:00
Stadium: Estadio Pedro Bidegain Round: 5
Referee: Fernando Espinoza Home Manager: Pedro Troglio Away Manager: Marcelo Gallardo
Head to Head
| Argentina Liga Profesional | 2021/10/17 23:15 | River Plate v San Lorenzo | L | 3-1 |
| Argentina Copa de la Liga Profesional | 2021/04/25 21:00 | River Plate v San Lorenzo | W | 1-2 |
| Argentina Superliga | 2019/12/09 00:45 | River Plate v San Lorenzo | W | 0-1 |
| Argentina Superliga | 2018/09/01 23:00 | San Lorenzo v River Plate | D | 1-1 |
| Argentina Superliga | 2018/05/15 00:15 | River Plate v San Lorenzo | L | 2-0 |
| Argentina Superliga | 2017/06/04 17:00 | San Lorenzo v River Plate | W | 2-1 |
| Argentina Liga Profesional | 2016/05/07 20:45 | San Lorenzo v River Plate | W | 2-1 |
| Argentina Torneo De Verano | 2016/01/27 01:10 | River Plate v San Lorenzo | L | 3-2 |
| Argentina Liga Profesional | 2015/04/05 19:00 | River Plate v San Lorenzo | L | 1-0 |
| Recopa Sudamericana | 2015/02/12 00:00 | San Lorenzo v River Plate | L | 0-1 |
| Recopa Sudamericana | 2015/02/07 00:00 | River Plate v San Lorenzo | L | 1-0 |
| Argentina Liga Profesional | 2014/09/01 00:30 | San Lorenzo v River Plate | L | 1-3 |
| Argentina Superliga | 2014/05/25 00:15 | San Lorenzo v River Plate | L | 0-1 |