[6] Sol de America 1-0 Guairena FC [8] 2022-02-20 21:00
Stadium: Estadio Luis Alfonso Giagni Round: 3
Referee: Giancarlos Juliadoza Home Manager: Juan Pablo Pumpido Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay Division Profesional | 2021/10/31 23:15 | Sol de America v Guairena FC | W | 3-0 |
| Paraguay Division Profesional | 2021/08/13 21:30 | Guairena FC v Sol de America | D | 1-1 |
| Paraguay Division Profesional | 2021/05/28 21:45 | Sol de America v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2021/03/22 21:15 | Guairena FC v Sol de America | D | 2-2 |
| Paraguay Division Profesional | 2020/11/02 22:30 | Sol de America v Guairena FC | D | 1-1 |
| Paraguay Division Profesional | 2020/08/23 23:00 | Sol de America v Guairena FC | W | 2-1 |
| Paraguay Division Profesional | 2020/02/07 21:00 | Guairena FC v Sol de America | L | 2-0 |
| Paraguay Cup | 2019/10/09 19:30 | Guairena FC v Sol de America | W | 1-3 |