[8] Guairena FC 2-3 Libertad Asuncion [2] 2022-04-02 22:00
Stadium: Estadio Parque del Guaira Round: 8
Referee: Juan Gabriel Benitez Home Manager: Troadio Daniel Duarte Away Manager: Daniel Garnero
Head to Head
| Paraguay Division Profesional | 2021/09/27 00:15 | Guairena FC v Libertad Asuncion | W | 2-1 |
| Paraguay Division Profesional | 2021/07/18 23:30 | Libertad Asuncion v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2021/04/12 00:30 | Libertad Asuncion v Guairena FC | L | 2-1 |
| Paraguay Division Profesional | 2021/02/24 22:00 | Guairena FC v Libertad Asuncion | W | 1-0 |
| Paraguay Division Profesional | 2020/10/17 23:15 | Guairena FC v Libertad Asuncion | L | 0-3 |
| Paraguay Division Profesional | 2020/09/05 21:30 | Libertad Asuncion v Guairena FC | L | 5-2 |
| Paraguay Division Profesional | 2020/02/28 23:00 | Guairena FC v Libertad Asuncion | W | 3-2 |