[11] Boston River 3-0 Cerro Largo [16] 2022-02-25 20:00
Stadium: Estadio Parque Artigas Round: 4
Referee: Antonio Garcia Home Manager: Ignacio Ithurralde Away Manager: Luis Danielo Nunez Maciel
Head to Head
| Uruguay Clausura | 2021/11/04 19:30 | Cerro Largo v Boston River | D | 1-1 |
| Uruguay Apertura | 2021/07/11 15:15 | Boston River v Cerro Largo | W | 1-0 |
| Uruguay Clausura | 2021/01/29 22:15 | Boston River v Cerro Largo | W | 2-1 |
| Uruguay Apertura | 2020/03/08 23:00 | Cerro Largo v Boston River | D | 0-0 |
| Uruguay Clausura | 2019/11/27 20:00 | Cerro Largo v Boston River | L | 1-0 |
| Uruguay Apertura | 2019/05/26 18:00 | Boston River v Cerro Largo | L | 2-3 |
| Uruguay Segunda | 2016/06/03 23:00 | Cerro Largo v Boston River | W | 0-1 |
| Uruguay Segunda | 2015/11/08 14:00 | Boston River v Cerro Largo | L | 1-2 |
| Uruguay Segunda | 2015/04/05 19:00 | Cerro Largo v Boston River | W | 2-3 |
| Uruguay Segunda | 2014/10/18 19:00 | Boston River v Cerro Largo | D | 0-0 |