[5] San Francisco FC 0-1 CD Universitario [6] 2022-02-26 01:00
Stadium: Estadio Agustín Muquita Sánchez Round: 4
Head to Head
| Panama LPF | 2021/10/30 20:00 | CD Universitario v San Francisco FC | W | 0-1 |
| Panama LPF | 2021/08/14 00:00 | San Francisco FC v CD Universitario | L | 0-1 |
| Panama LPF | 2021/04/24 00:00 | San Francisco FC v CD Universitario | D | 0-0 |
| Panama LPF | 2021/02/27 20:00 | CD Universitario v San Francisco FC | L | 3-2 |
| Panama LPF | 2020/11/14 20:00 | CD Universitario v San Francisco FC | W | 0-1 |
| Panama LPF | 2020/02/16 01:00 | San Francisco FC v CD Universitario | L | 0-2 |
| Panama LPF | 2019/11/16 23:00 | San Francisco FC v CD Universitario | D | 0-0 |
| Panama LPF | 2019/09/22 20:00 | CD Universitario v San Francisco FC | D | 2-2 |
| Panama LPF | 2019/04/06 02:00 | San Francisco FC v CD Universitario | D | 0-0 |
| Panama LPF | 2019/02/16 23:00 | CD Universitario v San Francisco FC | W | 1-2 |
| Panama LPF | 2018/11/04 00:00 | CD Universitario v San Francisco FC | W | 0-1 |
| Panama LPF | 2018/09/16 01:00 | San Francisco FC v CD Universitario | D | 1-1 |
| World Club Friendlies | 2018/07/10 02:14 | San Francisco FC v CD Universitario | L | 0-1 |
| Panama LPF | 2018/03/11 22:00 | CD Universitario v San Francisco FC | D | 0-0 |
| Panama LPF | 2018/01/20 02:00 | San Francisco FC v CD Universitario | D | 0-0 |
| Panama LPF | 2017/09/28 01:00 | CD Universitario v San Francisco FC | D | 1-1 |
| Panama LPF | 2017/07/29 01:00 | San Francisco FC v CD Universitario | D | 1-1 |
| Panama LPF | 2017/04/22 23:00 | CD Universitario v San Francisco FC | W | 1-2 |
| Panama LPF | 2017/02/18 02:00 | San Francisco FC v CD Universitario | D | 0-0 |
| Panama LPF | 2016/10/15 23:00 | CD Universitario v San Francisco FC | L | 2-0 |
| Panama LPF | 2016/08/13 23:00 | San Francisco FC v CD Universitario | L | 1-2 |
| Panama LPF | 2016/04/16 02:00 | San Francisco FC v CD Universitario | D | 0-0 |
| Panama LPF | 2016/02/20 23:00 | CD Universitario v San Francisco FC | D | 1-1 |
| Panama LPF | 2015/10/17 23:00 | CD Universitario v San Francisco FC | L | 2-1 |
| Panama LPF | 2015/08/22 02:00 | San Francisco FC v CD Universitario | L | 0-2 |
| Panama LPF | 2015/04/16 01:00 | CD Universitario v San Francisco FC | W | 0-2 |
| Panama LPF | 2015/02/12 01:00 | San Francisco FC v CD Universitario | W | 1-0 |
| Panama LPF | 2014/11/16 00:00 | CD Universitario v San Francisco FC | D | 1-1 |
| Panama LPF | 2014/11/08 02:00 | San Francisco FC v CD Universitario | W | 1-0 |
| Panama LPF | 2014/10/16 01:00 | San Francisco FC v CD Universitario | L | 0-1 |