[7] Real Santa Cruz 0-1 Always Ready [6] 2022-03-12 19:00
Stadium: Estadio Juan Carlos Duran Round: 6
Head to Head
| Bolivia Apertura | 2021/09/14 19:00 | Always Ready v Real Santa Cruz | L | 4-0 |
| Bolivia Apertura | 2021/04/03 19:00 | Real Santa Cruz v Always Ready | L | 2-3 |
| Bolivia Apertura | 2020/12/12 19:00 | Real Santa Cruz v Always Ready | L | 0-3 |
| Bolivia Apertura | 2020/02/09 19:00 | Always Ready v Real Santa Cruz | L | 6-0 |