[17] Reilly Opelka 6-1,6-4 Lorenzo Musetti [56] 2022-03-12 20:50
Stadium: Stadium 3 Round: 24 Ground: Hardcourt outdoor
Head to Head
| US Open | 2021/09/02 16:00 | Lorenzo Musetti v Reilly Opelka | 6-7,5-7,4-6 |
| ATP Rome | 2021/05/11 11:10 | Lorenzo Musetti v Reilly Opelka | 4-6,4-6 |