[6] Gigantes Carolina 105-82 Santurce [5] 2022-05-11 00:00
Stadium: Guillermo Angulo Coliseum Round: 1
Head to Head
| Puerto Rico Superior Nacional | 2021/09/15 00:00 | Gigantes Carolina v Santurce | L | 101-105 |
| Puerto Rico Superior Nacional | 2021/09/02 00:00 | Santurce v Gigantes Carolina | L | 96-82 |
| Puerto Rico Superior Nacional | 2021/08/10 00:00 | Santurce v Gigantes Carolina | L | 107-98 |
| Puerto Rico Superior Nacional | 2021/07/28 00:00 | Gigantes Carolina v Santurce | L | 75-84 |