| Guatemala LNV | 2021/11/21 00:00 | Farmaceuticos FSC v Eden United FSC | D | 2-2 |
| Guatemala LNV | 2021/11/19 01:00 | Eden United FSC v Farmaceuticos FSC | L | 2-7 |
| Guatemala LNV | 2021/11/05 02:00 | Farmaceuticos FSC v Eden United FSC | L | 6-1 |
| Guatemala LNV | 2021/01/09 20:00 | Farmaceuticos FSC v Eden United FSC | L | 9-3 |