Deportivo Santaní 3-0 River Plate Asuncion 2022-09-24 14:00
Stadium: Estadio Juan Jose Vazquez Round: 28
Head to Head
| Paraguay Division Intermedia | 2022/06/20 21:00 | River Plate Asuncion v Deportivo Santaní | L | 2-0 |
| Paraguay Division Profesional | 2019/11/30 23:00 | Deportivo Santaní v River Plate Asuncion | L | 0-1 |
| Paraguay Cup | 2019/09/17 20:30 | Deportivo Santaní v River Plate Asuncion | W | 1-0 |
| Paraguay Division Profesional | 2019/09/13 22:45 | River Plate Asuncion v Deportivo Santaní | L | 1-0 |
| Paraguay Division Profesional | 2019/04/03 22:30 | River Plate Asuncion v Deportivo Santaní | W | 1-2 |
| Paraguay Division Profesional | 2019/02/02 21:45 | Deportivo Santaní v River Plate Asuncion | D | 1-1 |
| Paraguay Division Intermedia | 2017/08/27 14:00 | River Plate Asuncion v Deportivo Santaní | L | 2-0 |
| Paraguay Division Intermedia | 2017/05/21 14:00 | Deportivo Santaní v River Plate Asuncion | W | 4-2 |
| Paraguay Division Intermedia | 2014/08/16 14:00 | River Plate Asuncion v Deportivo Santaní | W | 1-2 |
| Paraguay Division Intermedia | 2014/04/27 19:30 | Deportivo Santaní v River Plate Asuncion | W | 1-0 |