[14] SEA Seahawks 7-27 SF 49ers [27] 2022-09-18 20:05
Stadium: Levi's Stadium Round: 1
Home Manager: Kyle Shanahan Away Manager: Pete Carroll
Head to Head
| NFL | 2021/12/05 21:25 | SF 49ers v SEA Seahawks | W | 23-30 |
| NFL | 2021/10/03 20:05 | SEA Seahawks v SF 49ers | W | 28-21 |
| NFL | 2021/01/03 21:25 | SEA Seahawks v SF 49ers | W | 26-23 |
| NFL | 2020/11/01 21:25 | SF 49ers v SEA Seahawks | W | 27-37 |
| NFL | 2019/12/30 01:20 | SF 49ers v SEA Seahawks | L | 26-21 |
| NFL | 2019/11/12 01:15 | SEA Seahawks v SF 49ers | W | 27-24 |
| NFL Preseason | 2019/07/30 09:50 | SEA Seahawks v SF 49ers | L | 13-20 |
| NFL | 2018/12/16 21:05 | SEA Seahawks v SF 49ers | L | 23-26 |
| NFL | 2018/12/02 21:25 | SF 49ers v SEA Seahawks | W | 16-43 |
| NFL | 2017/11/26 21:05 | SEA Seahawks v SF 49ers | W | 24-13 |
| NFL | 2017/09/17 20:25 | SF 49ers v SEA Seahawks | W | 9-12 |
| NFL | 2017/01/01 21:25 | SEA Seahawks v SF 49ers | W | 25-23 |
| NFL | 2016/09/25 20:05 | SF 49ers v SEA Seahawks | W | 18-37 |
| NFL | 2015/11/22 21:25 | SEA Seahawks v SF 49ers | W | 29-13 |
| NFL | 2015/10/23 00:25 | SF 49ers v SEA Seahawks | W | 3-20 |
| NFL | 2014/12/14 21:25 | SEA Seahawks v SF 49ers | W | 17-7 |
| NFL | 2014/11/28 01:30 | SF 49ers v SEA Seahawks | W | 3-19 |