[16] Union Santa Fe 0-1 CA Independiente [23] 2022-09-19 22:00
Stadium: Estadio 15 de Abril Round: 20
Referee: Jorge Balino Home Manager: Gustavo Munua Away Manager: Julio Cesar Falcioni
Head to Head
| Argentina Liga Profesional | 2021/10/26 00:15 | CA Independiente v Union Santa Fe | L | 1-0 |
| Argentina Copa de la Liga Profesional | 2021/04/25 00:00 | Union Santa Fe v CA Independiente | D | 0-0 |
| Argentina Superliga | 2019/10/30 22:10 | Union Santa Fe v CA Independiente | D | 2-2 |
| Argentina Superliga | 2019/02/09 22:20 | CA Independiente v Union Santa Fe | L | 2-1 |
| Argentina Superliga | 2018/05/12 20:45 | Union Santa Fe v CA Independiente | W | 1-0 |
| Argentina Superliga | 2017/06/23 00:30 | Union Santa Fe v CA Independiente | L | 0-3 |
| Argentina Liga Profesional | 2015/03/14 23:10 | Union Santa Fe v CA Independiente | D | 1-1 |