[10] Atletico San Luis 1-2 Leon [13] 2022-07-03 22:00
Stadium: Alfonso Lastras Ramirez Round: 1
Referee: Fernando Hernandez Gomez Home Manager: Andre Jardine Away Manager: Renato Paiva
Head to Head
| Mexico Liga MX | 2022/04/09 22:00 | Atletico San Luis v Leon | W | 2-0 |
| Mexico Liga MX | 2021/10/02 22:00 | Leon v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2021/02/02 03:00 | Leon v Atletico San Luis | L | 3-1 |
| Mexico Liga MX | 2020/09/27 22:00 | Atletico San Luis v Leon | L | 0-2 |
| Mexico Liga MX | 2020/02/15 01:00 | Atletico San Luis v Leon | W | 3-1 |
| Mexico Liga MX | 2019/10/27 00:00 | Leon v Atletico San Luis | L | 3-2 |
| Mexico Cup | 2015/08/06 00:00 | Leon v Atletico San Luis | D | 3-3 |
| Mexico Cup | 2015/07/29 00:00 | Atletico San Luis v Leon | L | 1-2 |