[13] Real Santa Cruz 3-0 Universitario de Sucre [16] 2022-07-01 19:00
Stadium: Estadio Juan Carlos Duran Round: 1
Head to Head
| Bolivia Apertura | 2022/04/16 00:00 | Universitario de Sucre v Real Santa Cruz | W | 2-3 |
| Bolivia Apertura | 2022/02/06 16:00 | Real Santa Cruz v Universitario de Sucre | L | 0-1 |