[7] TSG Hoffenheim 4-1 Mainz [5] 2022-09-10 13:30
Stadium: PreZero Arena Round: 6
Referee: Daniel Schlager Home Manager: Andre Breitenreiter Away Manager: Bo Svensson
Head to Head
| Germany Bundesliga I | 2022/02/05 14:30 | Mainz v TSG Hoffenheim | L | 2-0 |
| Germany Bundesliga I | 2021/09/11 13:30 | TSG Hoffenheim v Mainz | L | 0-2 |
| Germany Bundesliga I | 2021/03/21 12:30 | TSG Hoffenheim v Mainz | L | 1-2 |
| Germany Bundesliga I | 2020/11/29 17:00 | Mainz v TSG Hoffenheim | D | 1-1 |
| Germany Bundesliga I | 2020/05/30 13:30 | Mainz v TSG Hoffenheim | W | 0-1 |
| Germany Bundesliga I | 2019/11/24 17:00 | TSG Hoffenheim v Mainz | L | 1-5 |
| Germany Bundesliga I | 2019/05/18 13:30 | Mainz v TSG Hoffenheim | L | 4-2 |
| Germany Bundesliga I | 2018/12/23 17:00 | TSG Hoffenheim v Mainz | D | 1-1 |
| Germany Bundesliga I | 2018/02/10 14:30 | TSG Hoffenheim v Mainz | W | 4-2 |
| Germany Bundesliga I | 2017/09/20 18:30 | Mainz v TSG Hoffenheim | W | 2-3 |
| Germany Bundesliga I | 2017/02/04 14:30 | TSG Hoffenheim v Mainz | W | 4-0 |
| Germany Bundesliga I | 2016/09/11 15:30 | Mainz v TSG Hoffenheim | D | 4-4 |
| Germany Bundesliga I | 2016/02/20 14:30 | TSG Hoffenheim v Mainz | W | 3-2 |
| Germany Bundesliga I | 2015/09/18 18:30 | Mainz v TSG Hoffenheim | L | 3-1 |
| Germany Bundesliga I | 2015/02/28 14:30 | TSG Hoffenheim v Mainz | W | 2-0 |
| Germany Bundesliga I | 2014/09/26 18:30 | Mainz v TSG Hoffenheim | D | 0-0 |