[8] Portsmouth 0-2 Milton Keynes Dons [23] 2022-12-17 15:00
Stadium: Fratton Park Round: 22
Referee: Samuel Barrott Home Manager: Danny Cowley Away Manager: Liam Manning
Head to Head
| England FA Cup | 2022/11/26 15:00 | Portsmouth v Milton Keynes Dons | W | 3-2 |
| England League 1 | 2022/01/15 15:00 | Portsmouth v Milton Keynes Dons | L | 1-2 |
| England League 1 | 2021/09/11 14:00 | Milton Keynes Dons v Portsmouth | L | 1-0 |
| England League 1 | 2021/04/17 11:30 | Milton Keynes Dons v Portsmouth | L | 1-0 |
| England League 1 | 2020/10/10 14:00 | Portsmouth v Milton Keynes Dons | W | 2-1 |
| England League 1 | 2020/02/25 19:45 | Portsmouth v Milton Keynes Dons | W | 3-1 |
| England League 1 | 2019/12/29 15:00 | Milton Keynes Dons v Portsmouth | L | 3-1 |
| England League 1 | 2018/02/10 15:00 | Milton Keynes Dons v Portsmouth | W | 1-2 |
| England League 1 | 2017/10/14 14:00 | Portsmouth v Milton Keynes Dons | W | 2-0 |