[21] Colchester 0-1 Grimsby [9] 2022-09-17 14:00
Stadium: JobServe Community Stadium Round: 10
Referee: Sunny Sukhvir Gill Home Manager: Wayne Brown Away Manager: Paul Hurst
Head to Head
| England League 2 | 2021/03/13 17:30 | Grimsby v Colchester | D | 0-0 |
| England League 2 | 2020/12/05 17:30 | Colchester v Grimsby | W | 2-1 |
| England League 2 | 2020/02/11 19:45 | Colchester v Grimsby | L | 2-3 |
| England League 2 | 2019/08/20 18:45 | Grimsby v Colchester | D | 2-2 |
| England League 2 | 2019/04/19 14:00 | Colchester v Grimsby | W | 1-0 |
| England League 2 | 2018/10/23 18:45 | Grimsby v Colchester | L | 1-0 |
| England League 2 | 2018/01/20 15:00 | Colchester v Grimsby | D | 1-1 |
| England League 2 | 2017/09/26 18:45 | Grimsby v Colchester | D | 2-2 |
| England League 2 | 2017/02/28 19:45 | Grimsby v Colchester | L | 1-0 |
| England League 2 | 2016/08/16 18:45 | Colchester v Grimsby | W | 3-2 |