[11] Atletico San Luis Women 0-2 Santos Laguna Women [13] 2022-10-16 22:00
Stadium: Alfonso Lastras Ramirez Round: 16
Head to Head
| Mexico Liga MX Femenil | 2022/03/20 23:00 | Atletico San Luis Women v Santos Laguna Women | L | 2-4 |
| Mexico Liga MX Femenil | 2021/11/02 03:00 | Santos Laguna Women v Atletico San Luis Women | L | 3-1 |
| Mexico Liga MX Femenil | 2021/03/21 23:00 | Atletico San Luis Women v Santos Laguna Women | D | 2-2 |
| Mexico Liga MX Femenil | 2020/11/10 01:00 | Santos Laguna Women v Atletico San Luis Women | L | 2-1 |
| Mexico Liga MX Femenil | 2020/01/07 02:00 | Atletico San Luis Women v Santos Laguna Women | W | 3-1 |
| Mexico Liga MX Femenil | 2019/10/24 23:00 | Santos Laguna Women v Atletico San Luis Women | D | 1-1 |