[13] Nacional Potosi 3-1 Real Santa Cruz [3] 2022-07-26 22:15
Stadium: Estadio Victor Agustín Ugarte Round: 6
Head to Head
| Bolivia Apertura | 2022/04/24 19:00 | Real Santa Cruz v Nacional Potosi | L | 3-2 |
| Bolivia Apertura | 2022/02/18 21:15 | Nacional Potosi v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2021/12/01 19:00 | Real Santa Cruz v Nacional Potosi | D | 1-1 |
| Bolivia Apertura | 2021/08/03 22:15 | Nacional Potosi v Real Santa Cruz | D | 2-2 |
| Bolivia Apertura | 2020/12/27 19:00 | Nacional Potosi v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2020/03/06 19:00 | Real Santa Cruz v Nacional Potosi | L | 2-1 |