[10] Eastern Michigan 45-23 Western Michigan [2] 2022-10-08 16:00
Stadium: Waldo Stadium Round: 1
Home Manager: Tim Lester Away Manager: Chris Creighton
Head to Head
| NCAAF | 2021/11/17 00:30 | Western Michigan v Eastern Michigan | W | 21-22 |
| NCAAF | 2020/12/05 19:00 | Eastern Michigan v Western Michigan | W | 53-42 |
| NCAAF | 2019/10/19 23:00 | Western Michigan v Eastern Michigan | W | 27-34 |
| NCAAF | 2018/10/06 16:00 | Eastern Michigan v Western Michigan | L | 24-27 |
| NCAAF | 2017/10/21 18:00 | Western Michigan v Eastern Michigan | L | 20-17 |
| NCAAF | 2016/10/22 19:30 | Eastern Michigan v Western Michigan | L | 31-45 |
| NCAAF | 2015/10/29 23:30 | Eastern Michigan v Western Michigan | L | 28-58 |
| NCAAF | 2014/11/15 19:00 | Western Michigan v Eastern Michigan | L | 51-7 |
| NCAAF | 2012/11/17 12:00 | Western Michigan v Eastern Michigan | W | 23-29 |
| NCAAF | 2011/10/22 12:00 | Eastern Michigan v Western Michigan | W | 14-10 |
| NCAAF | 2010/11/13 12:00 | Western Michigan v Eastern Michigan | L | 45-30 |
| NCAAF | 2009/11/14 12:00 | Eastern Michigan v Western Michigan | L | 14-35 |
| NCAAF | 2008/11/01 12:00 | Western Michigan v Eastern Michigan | L | 31-10 |
| NCAAF | 2007/10/27 12:00 | Eastern Michigan v Western Michigan | W | 19-2 |
| NCAAF | 2005/11/05 12:00 | Eastern Michigan v Western Michigan | L | 36-44 |
| NCAAF | 2004/10/16 12:00 | Western Michigan v Eastern Michigan | W | 31-35 |
| NCAAF | 2003/10/04 12:00 | Eastern Michigan v Western Michigan | L | 3-31 |
| NCAAF | 2002/11/09 12:00 | Western Michigan v Eastern Michigan | L | 33-31 |
| NCAAF | 2001/09/29 12:00 | Eastern Michigan v Western Michigan | L | 10-31 |
| NCAAF | 2000/11/18 12:00 | Western Michigan v Eastern Michigan | L | 28-0 |