[6] Virginia Tech 7-24 Duke [4] 2022-11-12 17:00
Stadium: Brooks Field at Wallace Wade Stadium Round: 1
Home Manager: Mike Elko Away Manager: Brent Pry
Head to Head
| NCAAF | 2021/11/13 20:30 | Duke v Virginia Tech | W | 17-48 |
| NCAAF | 2020/10/03 20:00 | Virginia Tech v Duke | W | 38-31 |
| NCAAF | 2019/09/27 23:00 | Duke v Virginia Tech | L | 45-10 |
| NCAAF | 2018/09/29 23:00 | Virginia Tech v Duke | W | 31-14 |
| NCAAF | 2017/10/28 23:20 | Duke v Virginia Tech | W | 3-24 |
| NCAAF | 2016/11/05 19:30 | Virginia Tech v Duke | W | 24-21 |
| NCAAF | 2015/10/24 19:30 | Virginia Tech v Duke | L | 43-45 |
| NCAAF | 2014/11/15 17:00 | Duke v Virginia Tech | W | 16-17 |
| NCAAF | 2012/10/13 12:00 | Virginia Tech v Duke | W | 41-20 |
| NCAAF | 2011/10/29 12:00 | Duke v Virginia Tech | W | 10-14 |
| NCAAF | 2010/10/23 12:00 | Virginia Tech v Duke | W | 44-7 |
| NCAAF | 2008/11/22 12:00 | Virginia Tech v Duke | W | 14-3 |
| NCAAF | 2007/10/13 12:00 | Duke v Virginia Tech | W | 14-43 |
| NCAAF | 2006/09/16 12:00 | Virginia Tech v Duke | W | 36-0 |
| NCAAF | 2005/09/10 12:00 | Duke v Virginia Tech | W | 0-45 |
| NCAAF | 2004/09/18 12:00 | Virginia Tech v Duke | W | 41-17 |