Grambling State 17-34 Southern 2022-11-26 19:00
Stadium: Caesars Superdome Round: 1
Home Manager: Eric Dooley Away Manager: Hue Jackson
Head to Head
| NCAAF | 2021/11/27 22:00 | Southern v Grambling State | W | 26-29 |
| NCAAF | 2021/04/17 18:30 | Grambling State v Southern | L | 7-49 |
| NCAAF | 2019/11/30 22:00 | Southern v Grambling State | L | 30-28 |
| NCAAF FCS | 2018/11/24 22:00 | Grambling State v Southern | L | 28-38 |
| NCAAF | 2017/11/25 22:00 | Grambling State v Southern | W | 30-21 |