[15] Real Santa Cruz 2-1 Nacional Potosi [4] 2022-10-08 19:00
Stadium: Estadio Juan Carlos Duran Round: 21
Head to Head
| Bolivia Clausura | 2022/07/26 22:15 | Nacional Potosi v Real Santa Cruz | L | 3-1 |
| Bolivia Apertura | 2022/04/24 19:00 | Real Santa Cruz v Nacional Potosi | W | 3-2 |
| Bolivia Apertura | 2022/02/18 21:15 | Nacional Potosi v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2021/12/01 19:00 | Real Santa Cruz v Nacional Potosi | D | 1-1 |
| Bolivia Apertura | 2021/08/03 22:15 | Nacional Potosi v Real Santa Cruz | D | 2-2 |
| Bolivia Apertura | 2020/12/27 19:00 | Nacional Potosi v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2020/03/06 19:00 | Real Santa Cruz v Nacional Potosi | W | 2-1 |