[8] Defensores de Banfield 3-0 River Plate [6] 2022-11-17 14:00
Stadium: Club Social y Deportivo Defensores de Banfield Round: 4
Head to Head
| Argentina Copa Metro | 2022/10/27 00:30 | River Plate v Defensores de Banfield | W | 1-3 |
| Argentina Division de Honor | 2022/07/21 00:00 | Defensores de Banfield v River Plate | L | 1-3 |
| Argentina Division de Honor | 2022/07/13 21:30 | River Plate v Defensores de Banfield | L | 3-1 |
| Argentina Division de Honor | 2022/07/07 00:00 | Defensores de Banfield v River Plate | W | 3-2 |
| Argentina Division de Honor | 2022/06/02 00:30 | Defensores de Banfield v River Plate | L | 0-3 |
| Argentina Serie A1 | 2022/03/17 19:00 | Defensores de Banfield v River Plate | L | 2-3 |
| Argentina Serie A1 | 2022/02/02 19:00 | River Plate v Defensores de Banfield | W | 2-3 |