Stadium: Winthrop Coliseum
Home Manager: Mark Prosser Away Manager: Dave Dickerson
| NCAAB | 2022/12/29 22:00 | Winthrop v USC Upstate | W | 62-70 |
| NCAAB | 2022/02/25 00:00 | USC Upstate v Winthrop | L | 59-89 |
| NCAAB | 2022/01/26 23:00 | Winthrop v USC Upstate | L | 95-91 |
| NCAAB | 2020/12/13 19:00 | Winthrop v USC Upstate | L | 107-77 |
| NCAAB | 2020/12/12 21:00 | Winthrop v USC Upstate | L | 95-77 |
| NCAAB | 2020/03/05 17:00 | USC Upstate v Winthrop | L | 70-106 |
| NCAAB | 2020/02/27 23:00 | Winthrop v USC Upstate | L | 90-82 |
| NCAAB | 2020/01/24 00:00 | USC Upstate v Winthrop | L | 53-79 |
| NCAAB | 2019/01/19 21:30 | Winthrop v USC Upstate | L | 82-72 |
| NCAAB | 2015/11/25 00:00 | USC Upstate v Winthrop | L | 78-79 |
| NCAAB | 2013/11/13 12:00 | Winthrop v USC Upstate | L | 82-74 |
| NCAAB | 2009/11/21 12:00 | Winthrop v USC Upstate | L | 49-46 |