Head to Head
| Copa Libertadores | 2022/05/20 00:00 | River Plate v Colo Colo | L | 4-0 |
| Copa Libertadores | 2022/04/28 00:00 | Colo Colo v River Plate | L | 1-2 |
| Copa Libertadores | 2022/05/20 00:00 | River Plate v Colo Colo | L | 4-0 |
| Copa Libertadores | 2022/04/28 00:00 | Colo Colo v River Plate | L | 1-2 |