Head to Head
| Ghana Premier League | 2022/12/21 15:00 | Karela United FC v Medeama SC | D | 1-1 |
| Ghana Premier League | 2022/03/18 15:00 | Karela United FC v Medeama SC | D | 1-1 |
| Ghana FA Cup | 2021/12/29 15:00 | Karela United FC v Medeama SC | D | 2-2 |
| Ghana Premier League | 2021/11/21 15:00 | Medeama SC v Karela United FC | L | 2-0 |
| Ghana FA Cup | 2021/06/20 15:00 | Karela United FC v Medeama SC | L | 1-2 |
| Ghana Premier League | 2021/06/05 15:00 | Medeama SC v Karela United FC | L | 1-0 |
| Ghana Premier League | 2021/01/31 15:00 | Karela United FC v Medeama SC | W | 2-0 |
| Ghana FA Cup | 2020/02/23 15:00 | Karela United FC v Medeama SC | L | 0-1 |
| Ghana Premier League | 2020/02/09 15:00 | Karela United FC v Medeama SC | D | 1-1 |
| World Club Friendlies | 2018/10/07 15:59 | Karela United FC v Medeama SC | L | 0-2 |
| Ghana Premier League | 2018/03/18 15:00 | Medeama SC v Karela United FC | L | 1-0 |
| World Club Friendlies | 2018/01/14 15:13 | Karela United FC v Medeama SC | D | 0-0 |