Stadium: Reitz Arena Round: 1
Home Manager: G.G. Smith Away Manager: Mike Brennan
| NCAAB | 2018/01/12 00:00 | Loyola Maryland v American | L | 65-76 |
| NCAAB | 2017/02/25 17:00 | Loyola Maryland v American | L | 62-64 |
| NCAAB | 2016/12/31 00:30 | American v Loyola Maryland | W | 66-68 |
| NCAAB | 2016/02/27 17:00 | American v Loyola Maryland | L | 67-66 |
| NCAAB | 2015/12/31 00:30 | Loyola Maryland v American | W | 75-67 |
| NCAAB | 2015/02/05 01:00 | American v Loyola Maryland | L | 64-49 |
| NCAAB | 2015/01/08 00:30 | Loyola Maryland v American | W | 56-53 |
| NCAAB | 2014/02/05 12:00 | Loyola Maryland v American | W | 62-58 |
| NCAAB | 2014/01/08 12:00 | American v Loyola Maryland | L | 65-51 |
| NCAAB | 2007/11/13 12:00 | Loyola Maryland v American | W | 71-67 |
| NCAAB | 2006/11/20 12:00 | American v Loyola Maryland | L | 81-74 |
| NCAAB | 2005/11/29 12:00 | Loyola Maryland v American | W | 68-60 |