[8] Resistencia FC 0-4 Guarani Asuncion [9] 2023-02-17 21:00
Stadium: Estadio Luis Alfonso Giagni Round: 4
Referee: Carlos P. Benitez Home Manager: Mario Vicente Jara Away Manager: Aureliano Torres
Head to Head
| Paraguay Division Profesional | 2022/10/03 22:00 | Guarani Asuncion v Resistencia FC | W | 0-1 |
| Paraguay Division Profesional | 2022/07/25 23:15 | Resistencia FC v Guarani Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2022/05/12 00:15 | Resistencia FC v Guarani Asuncion | L | 1-2 |
| Paraguay Division Profesional | 2022/02/26 21:15 | Guarani Asuncion v Resistencia FC | D | 3-3 |
| Paraguay Cup | 2018/11/20 23:15 | Guarani Asuncion v Resistencia FC | L | 6-5 |