BOS Red Sox 1-6 STL Cardinals 2018-02-27 18:05
Stadium: Fenway Park Round: 1
Home Manager: Dana LeVangie Away Manager: Mike Matheny
Head to Head
| MLB | 2017/08/16 23:10 | STL Cardinals v BOS Red Sox | W | 4-5 |
| MLB | 2017/08/15 23:10 | STL Cardinals v BOS Red Sox | W | 4-10 |
| MLB | 2017/05/18 00:15 | BOS Red Sox v STL Cardinals | W | 5-4 |
| MLB | 2017/05/17 00:15 | BOS Red Sox v STL Cardinals | W | 6-3 |
| MLB Spring Training | 2017/02/27 18:05 | BOS Red Sox v STL Cardinals | L | 2-7 |
| MLB Exhibition | 2016/03/21 17:05 | STL Cardinals v BOS Red Sox | W | 3-4 |
| MLB Exhibition | 2016/03/19 17:05 | BOS Red Sox v STL Cardinals | W | 3-1 |