[27] SD Padres 0-1 HOU Astros [4] 2018-04-07 23:10
Stadium: Minute Maid Park Round: 1
Home Manager: A.J. Hinch Away Manager: Darren Balsley
Head to Head
| MLB | 2018/04/07 00:10 | SD Padres v HOU Astros | W | 4-1 |
| MLB Exhibition | 2016/03/27 19:00 | SD Padres v HOU Astros | W | 21-6 |
| MLB Exhibition | 2016/03/27 01:00 | SD Padres v HOU Astros | L | 1-11 |
| MLB | 2015/04/29 19:40 | SD Padres v HOU Astros | L | 2-7 |