[1] Defensa y Justicia 2-1 Botafogo [2] 2023-08-30 22:00
Stadium: Florencio Sola Round: 3
Referee: Jhon Alexander Ospina Londono Home Manager: Julio Vaccari Away Manager: Bruno Lage
Head to Head
| Copa Sudamericana | 2023/08/23 22:00 | Botafogo v Defensa y Justicia | D | 1-1 |
| Copa Sudamericana | 2019/02/21 00:30 | Defensa y Justicia v Botafogo | L | 0-3 |
| Copa Sudamericana | 2019/02/06 23:30 | Botafogo v Defensa y Justicia | L | 1-0 |