Stadium: Tucker Stadium Round: 1
Home Manager: Dewayne Alexander Away Manager: Tom Matukewicz
| NCAAF | 2022/10/08 19:00 | Tennessee Tech v SE Missouri St | W | 20-34 |
| NCAAF | 2021/10/02 18:30 | SE Missouri St v Tennessee Tech | L | 17-28 |
| NCAAF | 2021/03/28 19:00 | Tennessee Tech v SE Missouri St | W | 21-24 |
| NCAAF | 2019/10/05 23:00 | Tennessee Tech v SE Missouri St | W | 37-43 |
| NCAAF | 2018/10/06 23:00 | SE Missouri St v Tennessee Tech | W | 70-38 |
| NCAAF | 2017/10/14 18:00 | SE Missouri St v Tennessee Tech | W | 31-3 |