CLE Indians 1-3 HOU Astros 2018-05-21 00:08
Stadium: Minute Maid Park Round: 1
Home Manager: A.J. Hinch Away Manager: Carl Willis
Head to Head
| MLB | 2018/05/19 20:10 | CLE Guardians v HOU Astros | W | 5-4 |
| MLB | 2018/05/19 00:10 | CLE Guardians v HOU Astros | L | 1-4 |
| MLB | 2017/05/21 18:10 | CLE Guardians v HOU Astros | W | 8-6 |
| MLB | 2017/05/20 20:10 | CLE Guardians v HOU Astros | W | 3-0 |
| MLB | 2017/05/20 00:10 | CLE Guardians v HOU Astros | W | 5-3 |
| MLB | 2017/04/27 22:10 | HOU Astros v CLE Guardians | W | 3-4 |
| MLB | 2017/04/26 22:10 | HOU Astros v CLE Guardians | W | 6-7 |
| MLB | 2017/04/25 22:10 | HOU Astros v CLE Guardians | L | 4-2 |
| MLB | 2016/09/08 16:10 | HOU Astros v CLE Guardians | W | 7-10 |
| MLB | 2016/09/07 22:54 | HOU Astros v CLE Guardians | W | 5-6 |
| MLB | 2016/09/06 22:45 | HOU Astros v CLE Guardians | L | 4-3 |
| MLB | 2016/09/05 22:53 | HOU Astros v CLE Guardians | L | 6-2 |