[5] Tottenham 3-1 Southampton [18] 2018-12-05 20:00
Stadium: Wembley Stadium Round: 15
Referee: Anthony Taylor Home Manager: Mauricio Pochettino Away Manager: Leslie Mark Hughes
Head to Head
| England Premier League | 2018/01/21 16:00 | Southampton v Tottenham | D | 1-1 |
| England Premier League | 2017/12/26 12:30 | Tottenham v Southampton | W | 5-2 |
| England Premier League | 2017/03/19 14:15 | Tottenham v Southampton | W | 2-1 |
| England Premier League | 2016/12/28 19:45 | Southampton v Tottenham | W | 1-4 |
| England Premier League | 2016/05/08 12:30 | Tottenham v Southampton | L | 1-2 |
| England Premier League | 2015/12/19 15:00 | Southampton v Tottenham | W | 0-2 |
| England Premier League | 2015/04/25 11:45 | Southampton v Tottenham | D | 2-2 |
| England Premier League | 2014/10/05 13:05 | Tottenham v Southampton | W | 1-0 |