[10] Crystal Palace 0-2 Southampton [17] 2018-09-01 14:00
Stadium: Selhurst Park Round: 4
Referee: Martin Atkinson Home Manager: Roy Hodgson Away Manager: Leslie Mark Hughes
Head to Head
| England Premier League | 2018/01/02 19:45 | Southampton v Crystal Palace | W | 1-2 |
| England Premier League | 2017/09/16 11:30 | Crystal Palace v Southampton | L | 0-1 |
| England Premier League | 2017/04/05 18:45 | Southampton v Crystal Palace | L | 3-1 |
| England Premier League | 2016/12/03 15:00 | Crystal Palace v Southampton | W | 3-0 |
| England EFL Cup | 2016/09/21 18:45 | Southampton v Crystal Palace | L | 2-0 |
| England Premier League | 2016/05/15 14:00 | Southampton v Crystal Palace | L | 4-1 |
| England FA Cup | 2016/01/09 15:00 | Southampton v Crystal Palace | W | 1-2 |
| England Premier League | 2015/12/12 15:00 | Crystal Palace v Southampton | W | 1-0 |
| England Premier League | 2015/03/03 19:45 | Southampton v Crystal Palace | L | 1-0 |
| England FA Cup | 2015/01/24 15:00 | Southampton v Crystal Palace | W | 2-3 |
| England Premier League | 2014/12/26 15:00 | Crystal Palace v Southampton | L | 1-3 |