[10] Toluca 2-1 Santos Laguna [4] 2018-09-02 17:00
Stadium: Estadio Nemesio Diez Round: 8
Referee: Marco Antonio Ortiz Nava Home Manager: Hernan Cristante Away Manager: Salvador Reyes
Head to Head
| Mexico Liga MX | 2018/05/21 00:00 | Toluca v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2018/05/18 01:00 | Santos Laguna v Toluca | L | 2-1 |
| Mexico Liga MX | 2018/02/18 18:00 | Toluca v Santos Laguna | W | 2-0 |
| Mexico Cup | 2018/02/08 02:30 | Toluca v Santos Laguna | W | 2-0 |
| Mexico Cup | 2018/01/25 01:00 | Santos Laguna v Toluca | L | 2-1 |
| Mexico Liga MX | 2017/09/10 23:30 | Santos Laguna v Toluca | D | 0-0 |
| Mexico Liga MX | 2017/05/14 02:00 | Toluca v Santos Laguna | L | 1-3 |
| Mexico Liga MX | 2017/05/11 02:30 | Santos Laguna v Toluca | W | 1-4 |
| Mexico Liga MX | 2017/05/07 23:00 | Santos Laguna v Toluca | D | 2-2 |
| Mexico Liga MX | 2016/11/20 18:00 | Toluca v Santos Laguna | L | 1-2 |
| Mexico Liga MX | 2016/04/02 02:30 | Toluca v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2015/10/04 00:00 | Santos Laguna v Toluca | D | 0-0 |
| Mexico Liga MX | 2015/02/15 18:00 | Toluca v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2014/08/23 02:30 | Santos Laguna v Toluca | L | 3-0 |