East Carolina 13-20 South Florida 2018-09-23 00:00
Stadium: Raymond James Stadium Round: 1
Home Manager: Charlie Strong Away Manager: Scottie Montgomery
Head to Head
| NCAAF | 2017/09/30 16:00 | East Carolina v South Florida | L | 31-61 |
| NCAAF | 2016/10/08 16:00 | South Florida v East Carolina | L | 38-22 |
| NCAAF | 2015/11/08 00:30 | East Carolina v South Florida | L | 17-22 |
| NCAAF | 2014/10/11 23:00 | South Florida v East Carolina | W | 17-28 |
| NCAAF Bowl Games | 2006/12/23 12:00 | East Carolina v South Florida | L | 7-24 |
| NCAAF | 2004/11/13 12:00 | South Florida v East Carolina | L | 41-17 |
| NCAAF | 2003/11/08 12:00 | East Carolina v South Florida | L | 37-38 |
| NCAAF | 2002/10/19 12:00 | East Carolina v South Florida | L | 30-46 |