Maria Camila Osorio

Grand Slam performance Singles:

• Australian Open: –
• French Open: SF (2019)
• Wimbledon: 3R (2017)
• US Open: W (2019)

Doubles:

• Australian Open: –
• French Open: QF (2017)
• Wimbledon: 2R (2017, 2019)
• US Open: QF (2018)

She won the girls' singles title at the 2019 US Open. In the final, she defeated Alexandra Yepifanova, losing only one game. On the ITF Junior Circuit, Osorio advanced to the world No. 1 in September 2019.

At the 2018 Summer Youth Olympics, she won the bronze medal in girls' singles and a silver medal in mixed doubles, alongside Nicolás Mejía.

Osorio made her WTA 1000 debut at the 2021 BNP Paribas Open in Indian Wells. In April 2021, while ranked world No. 180, Osorio won her first singles title at the Copa Colsanitas in her native Colombia, defeating Tamara Zidanšek in the final. She followed up with a semifinal appearance at the Charleston Open the following week.

In May, she reached her third straight clay-court semifinal at the Serbia Open, entering the top 100 as a result. She came through the qualifying at the French Open to make her Major debut. However, she lost in the first round to Madison Brengle.

In June, she again qualified for the main draw at the Wimbledon Championships. She reached the third round by defeating fellow-qualifier Anna Kalinskaya and 32nd seed Ekaterina Alexandrova before losing to second seed Aryna Sabalenka.

Osorio started at the US Open defeating Ivana Jorović in the first round of the tournament, before losing to Ons Jabeur in the second. Osorio completed her first professional season by reaching the final of the Tenerife Open, where she eventually lost to Ann Li. She later revealed in an interview that she sustained an abdominal injury which affected her in the final round of the tournament. Her success at the tournament saw her reach a new career high of No. 53 on 25 October 2021, finishing the season ranked No. 55.

Osorio gained direct acceptance at the Monterrey Open. She reached her third WTA Tour-level singles final, losing to second seed and 2021 US Open runner-up, Leylah Fernandez, after having multiple match points.

She reached a career-high ranking of No. 33 on 4 April 2022.

Osorio won her first match at the Australian Open defeating Panna Udvardy.

Osorio gained direct acceptance at the Lyon Open. She reached her first semifinal of the season where she defeated local and third seed of the tournament, Alizé Cornet, in the first round, Jule Niemeier in the second round and Linda Nosková in the quarterfinals. She lost her semifinal match to top seed Caroline Garcia, in straight sets.

Ranked No. 70 at the Monterrey Open, Osorio retired in the first round in the second set against Mayar Sherif. As a result of not being able to defend her points from the previous year final, she fell 30 positions down to top 100 on 6 March 2023.

Ranked No. 115, she received a wildcard for the main draw of the Madrid Open. She reached the third round of a WTA 1000 for the first time in her career, defeating Clara Burel and 32nd seed Marta Kostyuk. She qualified for the next WTA 1000, the Italian Open, and won her first-round match against Varvara Gracheva, after saving three match points. Next, she defeated 29th seed Petra Martić to reach back to back third rounds at a WTA 1000 level. She reached her first fourth round at a WTA 1000 level with a Top 5 win over Caroline Garcia, avenging her semifinal loss in Lyon and becoming the first Colombian woman to reach the round of 16 at a WTA 1000 tournament. As a result, she returned to the top 85 on 22 May 2023. As the top qualifying seed, she entered the French Open as a lucky loser, and defeated Ana Bogdan in the first round.

At her home tournament, the Copa Colsanitas in Bogotá, Colombia, Osorio reached the semifinals for the third time, defeating qualifiers Marina Stakusic and Anca Todoni and then second seed and defending champion Tatjana Maria. She reached her second final at the tournament defeating Sara Errani. She lifted her second title at the tournament defeating top seed Marie Bouzková in straight sets. As a result, she returned to the top 65 in the rankings.

At the WTA 500 2024 Guadalajara Open Akron, she defeated Hailey Baptiste and seventh seed Veronika Kudermetova in three sets, coming from 0-5 games in the third set and reeling off seven games in a row to win the match and reach the quarterfinals. Next she defeated Kamilla Rakhimova in straight sets to reach her first WTA semifinal at the 500-level, becoming the first Colombian to accomplish the feat. She lost in the last four to Olivia Gadecki.