| NCAAF | 11/13 18:30 | 1 | Capital Crusaders v Muskingum Muskies | W | 27-46 | |
| NCAAF | 11/06 17:30 | 1 | Mount Union v Muskingum Muskies | L | 73-7 | |
| NCAAF | 10/30 17:30 | 1 | Muskingum Muskies v Heidelberg Student Princes | L | 14-49 | |
| NCAAF | 10/23 18:00 | 1 | Otterbein Cardinals v Muskingum Muskies | W | 14-31 | |
| NCAAF | 10/16 20:00 | 1 | Muskingum Muskies v Baldwin Wallace Yellow Jackets | L | 10-49 | |
| NCAAF | 10/02 17:30 | 1 | John Carroll Blue Streaks v Muskingum Muskies | L | 29-7 | |
| NCAAF | 09/25 17:30 | 1 | Muskingum Muskies v Wilmington Quakers | W | 62-14 | |
| NCAAF | 09/18 23:00 | 1 | Marietta Pioneers v Muskingum Muskies | L | 18-0 | |
| NCAAF | 09/11 23:00 | 1 | Muskingum Muskies v Ohio Northern Polar Bears | W | 33-31 | |
| NCAAF | 09/04 20:00 | 1 | Muskingum Muskies v Waynesburg Yellow Jackets | W | 49-6 | |
| NCAAF | 11/16 18:30 | 1 | Capital Crusaders v Muskingum Muskies | W | 14-51 | |
| NCAAF | 11/09 18:30 | 1 | Mount Union v Muskingum Muskies | L | 51-3 | |
| NCAAF | 11/02 17:30 | 1 | Muskingum Muskies v Heidelberg Student Princes | L | 21-59 | |
| NCAAF | 10/26 17:30 | 1 | Otterbein Cardinals v Muskingum Muskies | L | 18-10 | |
| NCAAF | 10/19 18:00 | 1 | Muskingum Muskies v Baldwin Wallace Yellow Jackets | L | 28-42 | |
| NCAAF | 10/05 17:30 | 1 | John Carroll Blue Streaks v Muskingum Muskies | L | 31-10 | |
| NCAAF | 09/28 17:30 | 1 | Muskingum Muskies v Wilmington Quakers | W | 38-21 | |
| NCAAF | 09/21 23:00 | 1 | Marietta Pioneers v Muskingum Muskies | L | 31-25 | |
| NCAAF | 09/14 17:30 | 1 | Muskingum Muskies v Ohio Northern Polar Bears | L | 10-39 | |
| NCAAF | 09/07 17:30 | 1 | Muskingum Muskies v Waynesburg Yellow Jackets | W | 31-20 | |
| NCAAF | 11/10 18:30 | 1 | Muskingum Muskies v Capital Crusaders | L | 28-33 | |
| NCAAF | 11/03 17:30 | 1 | Muskingum Muskies v Mount Union | L | 10-52 | |
| NCAAF | 10/27 17:30 | 1 | Heidelberg Student Princes v Muskingum Muskies | W | 14-41 | |
| NCAAF | 10/20 18:00 | 1 | Muskingum Muskies v Otterbein Cardinals | W | 21-14 | |
| NCAAF | 10/13 17:30 | 1 | Baldwin Wallace Yellow Jackets v Muskingum Muskies | L | 44-7 | |
| NCAAF | 09/29 17:30 | 1 | Muskingum Muskies v John Carroll Blue Streaks | L | 7-44 | |
| NCAAF | 09/22 18:00 | 1 | Wilmington Quakers v Muskingum Muskies | W | 24-31 | |
| NCAAF | 09/15 17:30 | 1 | Muskingum Muskies v Marietta Pioneers | L | 20-46 | |
| NCAAF | 09/08 17:30 | 1 | Ohio Northern Polar Bears v Muskingum Muskies | L | 42-14 | |
| NCAAF | 09/01 17:30 | 1 | Waynesburg Yellow Jackets v Muskingum Muskies | W | 24-31 |