| NCAAF | 12/07 18:00 | 3 | Valdosta State v Virginia Union Panthers | L | 49-14 | |
| NCAAF | 11/30 18:00 | 124 | Lenoir Rhyne Bears v Virginia Union Panthers | W | 12-44 | |
| NCAAF | 11/23 18:00 | 122 | Wingate Bulldogs v Virginia Union Panthers | W | 31-34 | |
| NCAAF | 11/16 20:00 | 1 | Virginia State Trojans v Virginia Union Panthers | W | 13-17 | |
| NCAAF | 11/09 18:00 | 1 | Virginia State Trojans v Virginia Union Panthers | L | 35-28 | |
| NCAAF | 11/02 17:00 | 1 | Virginia Union Panthers v Bluefield State | W | 91-0 | |
| NCAAF | 10/26 17:00 | 1 | Bowie State Bulldogs v Virginia Union Panthers | W | 28-56 | |
| NCAAF | 10/19 17:00 | - | Lincoln University v Virginia Union Panthers | W | 12-63 | |
| NCAAF | 10/12 17:00 | 1 | Virginia Union Panthers v Elizabeth City State Vikings | W | 35-0 | |
| NCAAF | 10/05 17:00 | 1 | Virginia Union Panthers v Winston-Salem State | W | 31-13 | |
| NCAAF | 09/28 17:00 | 1 | Virginia Union Panthers v Shaw Bears | W | 42-7 | |
| NCAAF | 09/21 22:00 | 1 | Johnson C Smith GB v Virginia Union Panthers | L | 21-16 | |
| NCAAF | 09/07 22:00 | 1 | Hampton v Virginia Union Panthers | L | 33-21 | |
| NCAAF | 08/31 19:00 | 1 | Kentucky Thorobreds v Virginia Union Panthers | W | 7-69 | |
| NCAAF | 11/18 17:00 | 7 | Kutztown Golden Bears v Virginia Union Panthers | L | 38-14 | |
| NCAAF | 11/11 20:00 | 1 | Fayetteville State Broncos v Virginia Union Panthers | W | 10-21 | |
| NCAAF | 11/04 17:00 | 1 | Virginia Union Panthers v Virginia State Trojans | W | 30-20 | |
| NCAAF | 10/28 17:00 | 1 | Bluefield State v Virginia Union Panthers | W | 12-57 | |
| NCAAF | 10/21 17:00 | 1 | Virginia Union Panthers v Lincoln University Lions | W | 57-0 | |
| NCAAF | 10/14 17:00 | 1 | Virginia Union Panthers v Bowie State Bulldogs | W | 52-3 | |
| NCAAF | 10/07 17:00 | 1 | Elizabeth City State Vikings v Virginia Union Panthers | W | 20-42 | |
| NCAAF | 09/30 17:00 | 1 | St Augustines Falcons v Virginia Union Panthers | W | 7-47 | |
| NCAAF | 09/23 22:00 | 1 | Virginia Union Panthers v Fayetteville State Broncos | L | 7-10 | |
| NCAAF | 09/16 22:00 | 1 | Livingstone C. BB v Virginia Union Panthers | W | 20-28 | |
| NCAAF | 09/09 17:00 | 1 | Shaw Bears v Virginia Union Panthers | W | 13-26 | |
| NCAAF | 09/03 20:00 | 1 | Morehouse College Maroon Tigers v Virginia Union Panthers | W | 13-45 | |
| NCAAF | 11/19 18:00 | 7 | Virginia Union Panthers v Wingate Bulldogs | L | 7-32 | |
| NCAAF | 11/05 16:00 | 1 | Virginia State Trojans v Virginia Union Panthers | W | 21-33 | |
| NCAAF | 10/29 17:00 | 1 | Virginia Union Panthers v Chowan Hawks | L | 21-26 | |
| NCAAF | 10/22 16:00 | 1 | Lincoln University v Virginia Union Panthers | W | 20-45 |