| NCAAF | 11/16 18:00 | 1 | Lagrange Panthers v Southern Virginia Knights | L | 50-24 | |
| NCAAF | 11/09 18:00 | 1 | Southern Virginia Knights v Huntingdon Hawks | L | 0-51 | |
| NCAAF | 10/26 17:00 | 1 | Southern Virginia Knights v Nc Wesleyan Battling Bishops | L | 31-34 | |
| NCAAF | 10/19 19:00 | 1 | Methodist Monarchs v Southern Virginia Knights | W | 17-21 | |
| NCAAF | 10/12 17:00 | 1 | Belhaven Blazers v Southern Virginia Knights | L | 38-17 | |
| NCAAF | 10/05 17:00 | 1 | Southern Virginia Knights v Brevard Tornados | L | 21-55 | |
| NCAAF | 09/28 16:00 | 1 | Greensboro Pride v Southern Virginia Knights | L | 42-23 | |
| NCAAF | 09/21 17:00 | 1 | Southern Virginia Knights v Maryville Scots | L | 6-54 | |
| NCAAF | 09/14 18:00 | 1 | Bridgewater Eagles v Southern Virginia Knights | L | 80-0 | |
| NCAAF | 09/07 17:00 | - | The Apprentice School Builders v Southern Virginia Knights | L | 44-9 | |
| NCAAF | 11/11 18:00 | 1 | Maryville Scots v Southern Virginia Knights | L | 48-10 | |
| NCAAF | 11/04 16:00 | 1 | Southern Virginia Knights v Belhaven Blazers | L | 7-61 | |
| NCAAF | 10/28 17:00 | 1 | Southern Virginia Knights v Greensboro Pride | L | 7-47 | |
| NCAAF | 10/21 16:00 | 1 | Nc Wesleyan Battling Bishops v Southern Virginia Knights | L | 34-7 | |
| NCAAF | 10/07 17:00 | 1 | Brevard Tornados v Southern Virginia Knights | L | 49-28 | |
| NCAAF | 09/30 17:00 | 1 | Southern Virginia Knights v Lagrange Panthers | W | 52-26 | |
| NCAAF | 09/23 17:00 | 1 | Methodist Monarchs v Southern Virginia Knights | L | 27-21 | |
| NCAAF | 09/16 17:00 | 1 | Southern Virginia Knights v Randolph Macon Yellow Jackets | L | 10-51 | |
| NCAAF | 09/09 17:00 | 1 | Southern Virginia Knights v Bridgewater Eagles | L | 9-35 | |
| NCAAF | 09/02 21:00 | 1 | Christopher Newport Captains v Southern Virginia Knights | L | 45-0 | |
| NCAAF | 11/12 18:00 | 1 | Southern Virginia Knights v Brevard Tornados | L | 27-41 | |
| NCAAF | 11/05 17:00 | 1 | Lagrange Panthers v Southern Virginia Knights | W | 21-35 | |
| NCAAF | 10/29 17:00 | 1 | Southern Virginia Knights v Methodist Monarchs | L | 23-36 | |
| NCAAF | 10/22 17:00 | 1 | Belhaven Blazers v Southern Virginia Knights | L | 42-6 | |
| NCAAF | 10/15 17:00 | 1 | Southern Virginia Knights v Maryville Scots | L | 7-45 | |
| NCAAF | 10/08 16:00 | 1 | Greensboro Pride v Southern Virginia Knights | L | 38-28 | |
| NCAAF | 09/24 17:00 | 1 | Southern Virginia Knights v Nc Wesleyan Battling Bishops | L | 13-14 | |
| NCAAF | 09/17 17:00 | 1 | Randolph Macon Yellow Jackets v Southern Virginia Knights | L | 47-20 | |
| NCAAF | 09/10 18:00 | 1 | Bridgewater Eagles v Southern Virginia Knights | L | 58-10 | |
| NCAAF | 09/01 23:00 | 1 | Southern Virginia Knights v Wilmington Quakers | L | 27-52 |