| Colombia Regional League | 03/23 17:00 | - | Talento y Vida v Atletico Nacional Medellin Reserves | W | 2-5 | |
| Colombia Regional League | 03/07 17:11 | - | Soccer Law v Atletico Nacional Medellin Reserves | D | 1-1 | |
| Colombia Regional League | 12/03 19:37 | - | Ferrovalvulas FC v Atletico Nacional Medellin Reserves | W | 1-2 | |
| Colombia Regional League | 12/01 17:32 | - | SD Atletico Nacional Reserves v Deportivo Alexis Garcia | W | 2-0 | |
| Colombia Regional League | 11/25 17:00 | - | SD Atletico Nacional Reserves v Envigado FC Reserves | W | 3-1 | |
| Colombia Regional League | 11/19 19:20 | - | Atletico Nacional Medellin Reserves v CD Gallegol | W | 1-0 | |
| Colombia Regional League | 11/14 19:00 | - | SD Atletico Nacional Reserves v Real Santuario | W | 4-0 | |
| Colombia Regional League | 10/24 15:13 | - | Real Santuario v Atletico Nacional Medellin Reserves | L | 3-2 | |
| Colombia Regional League | 08/29 15:15 | - | Club Deportivo La Chalaca v Nacional Reserves | W | 1-2 | |
| Colombia Regional League | 08/03 17:00 | - | Sellos Colombianos v Atletico Nacional Medellin Reserves | D | 2-2 | |
| Colombia Regional League | 07/03 21:24 | - | Estudiantes de Medellin v Atletico Nacional Medellin Reserves | W | 0-4 | |
| Colombia Regional League | 06/10 13:00 | - | Envigado FC Reserves v Atletico Nacional Medellin Reserves | L | 2-0 | |
| Colombia Regional League | 05/24 15:00 | - | FC Leones Reserves v Atletico Nacional Medellin Reserves | L | 2-1 | |
| Colombia Regional League | 05/10 17:13 | - | Universidad de Antioquia v Atletico Nacional Medellin Reserves | W | 0-1 | |
| Colombia Regional League | 04/23 16:00 | - | Independiente Sabaneta v Atletico Nacional Medellin Reserves | D | 0-0 | |
| Colombia Regional League | 03/22 17:14 | - | Talento y Vida v Atletico Nacional Medellin Reserves | W | 0-5 | |
| Colombia Regional League | 11/27 19:24 | - | Atletico Nacional Medellin Reserves v Deportivo Alexis Garcia | W | 2-0 | |
| Colombia Regional League | 09/04 21:14 | - | Rionegro Aguilas Reserves v Atletico Nacional Medellin Reserves | L | 2-1 | |
| Colombia Regional League | 07/31 21:06 | - | Inder Girardota v Atletico Nacional Medellin Reserves | W | 1-2 | |
| Colombia Regional League | 07/04 13:00 | - | Atletico Nacional Medellin Reserves v Deportivo Alexis Garcia | W | 1-0 | |
| Colombia Regional League | 06/11 17:00 | - | Club Deportivo La Chalaca v Atletico Nacional Medellin Reserves | L | 1-0 | |
| Colombia Regional League | 11/26 17:03 | - | Atletico Nacional Medellin Reserves v FC Leones Reserves | D | 0-0 |