Clube Esportivo Dom Bosco, commonly known as Dom Bosco, are a Brazilian football team from Cuiabá. They won the Campeonato Matogrossense six times and competed in the Série A three times. Dom Bosco are the oldest club from Mato Grosso state.
They were founded on January 4, 1925, being the oldest club from Mato Grosso state. Dom Bosco won the Campeonato Matogrossense for the first time in 1958. The club competed in the Série A in 1977, 1978 and in 1979. They finished in the last place in 1977.