Gallos de Sancti Spíritus (English: Sancti Spíritus Roosters) is a baseball team in the Cuban National Series. The team won the series championship in 1978–79. The Gallos have advanced to the National Series semifinals in each of the past two seasons; 2004–05 and 2005–06.
Three Sancti Spíritus players were part of Cuba's team at the 2006 World Baseball Classic: Frederich Cepeda, Yulieski Gourriel and Eriel Sánchez.