Lena Papadakis (née Rüffer; born 23 August 1998) is a German tennis player.
Papadakis has a career-high singles ranking by the WTA of world No. 250, achieved in January 2023, and a career-high doubles ranking of No. 121, reached in October 2024.
She made her WTA Tour debut at the 2015 Nürnberger Versicherungscup, partnering Katharina Gerlach in the doubles draw.