| 1 | 2 | H | 3 | 4 | F |
|---|---|---|---|---|---|
| 14 | 7 | 21 | 14 | 13 | 48 |
| 0 | 14 | 14 | 7 | 21 | 42 |
Lineups
| BUF Bills | DET Lions |
| Lineup | |
|---|---|
| 57 - DE - A.J. Epenesa | Brock Wright - TE - 89 |
| 85 - TE - Quintin Morris | Jameson Williams - WR - 9 |
| 29 - DB - Brandon Codrington | Brandon Joseph - FS - 12 |
| 69 - LS - Reid Ferguson | Sam LaPorta - TE - 87 |
| 90 - DT - DeWayne Carter | Jack Campbell - Left back - 46 |
| 5 - Center back - Kaiir Elam | Al-Quadin Muhammad - DE - 69 |
| 76 - OL - David Edwards | Taylor Decker - OT - 68 |
| 2 - K - Tyler Bass | Penei Sewell - OT - 58 |
| 79 - OT - Spencer Brown | Kerby Joseph - DB - 31 |
| 26 - Right back - Ty Johnson | Josh Paschal - DE - 93 |
| 92 - DT - Daquan Jones | Carlton Davis - Center back - 23 |
| 24 - SAF - Cole Bishop | Ben Niemann - Left back - 51 |
| - WR - Keon Coleman | David Montgomery - Right back - 5 |
| 8 - Pivot - Sam Martin | Ezekiel Turner - Left back - 47 |
| 18 - WR - Amari Cooper | Sione Vaki - Right back - 33 |
| 40 - OLB - Von Miller | Craig Reynolds - Right back - 13 |
| 62 - OL - Sedrick Van Pran-Granger | Christian Mahogany - OL - 73 |
| 97 - DE - Jordan Phillips | Shane Zylstra - TE - 84 |
| 27 - SAF - Kareem Jackson | Levi Onwuzurike - DT - 91 |
| 50 - DE - Gregory Rousseau | Alim McNeill - DT - 54 |
| 66 - OG - Connor McGovern | Amon-Ra St. Brown - WR - 14 |
| 70 - OL - Alec Anderson | Terrion Arnold - DB - |
| 4 - Right back - James Cook | Jacob Bates - K - 39 |
| 7 - Center back - Taron Johnson | Jahmyr Gibbs - Right back - 26 |
| 43 - Left back - Terrel Bernard | Jonah Williams - DE - 78 |
| 74 - OL - Ryan Van Demark | Kindle Vildor - Center back - 29 |
| 46 - Center back - Ja'Marcus Ingram | Amik Robertson - Center back - 21 |
| 54 - Left back - Baylon Spector | Brian Branch - DB - 32 |
| 88 - TE - Dawson Knox | Abraham Beauplan - Left back - 48 |
| 39 - Center back - Cam Lewis | Hogan Hatten - Left back - 49 |
| 91 - DT - Ed Oliver | Maurice Alexander - WR - 1 |
| 17 - QB - Josh Allen | David Long - Left back - 43 |
| 10 - WR - Khalil Shakir | Frank Ragnow - OL - 77 |
| 98 - DT - Austin Johnson | Dan Skipper - OT - 70 |
| 44 - Left back - Joe Andreessen | Pat O'Connor - DE - 95 |
| 73 - OT - Dion Dawkins | Za'Darius Smith - Left back - 99 |
| 64 - Guard - O'Cyrus Torrence | Kwon Alexander - OLB - 10 |
| 56 - Left back - Javon Solomon | Graham Glasgow - Guard - 60 |
| 42 - Left back - Dorian Williams | Jared Goff - QB - 16 |
| 22 - Right back - Ray Davis | Tim Patrick - WR - 17 |
| 94 - DE - Dawuane Smoot | D.J. Reader - DT - 98 |
| 1 - WR - Curtis Samuel | Michael Niese - OL - 62 |
| 13 - WR - Mack Hollins | Jamal Adams - SS - 25 |
| 58 - Left back - Matt Milano | Khalil Dorsey - Center back - 30 |
| 86 - TE - Dalton Kincaid | Allen Robinson - WR - 8 |
| 47 - DB - Christian Benford | Jack Fox - Pivot - 3 |
| 41 - TE - Reggie Gilliam | Kevin Zeitler - OG - 71 |
| Substitutes | |
Events
- 1st Drive - First Down - No #DET Lions #Q1#13'#69#15
- 1st Drive - Punt #DET Lions #Q1#13'#69#15
- 1st Score - Touchdown - Allen #BUF Bills #Q1#10'#256#15
- 1st Quarter Race to 6 - #BUF Bills #Q1#10'#256#15
- 2nd Drive - First Down - Yes #BUF Bills #Q1#10'#256#15
- 2nd Drive - Offensive Touch Down - #BUF Bills #Q1#10'#256#15
- 1 PAT - #BUF Bills #Q1#10'#256#15
- 3rd Drive - First Down - Yes #DET Lions #Q1#7'#449#15
- 3rd Drive - Punt #DET Lions #Q1#7'#449#15
- 2nd Score - Touchdown - Allen #BUF Bills #Q1#2'#775#15
- 1st Quarter Race to 12 - #BUF Bills #Q1#2'#775#15
- Race to 10 - #BUF Bills #Q1#2'#775#15
- 4th Drive - First Down - Yes #BUF Bills #Q1#2'#775#15
- 4th Drive - Offensive Touch Down - #BUF Bills #Q1#2'#775#15
- 1 PAT - #BUF Bills #Q1#2'#775#15
- Score After 1st Quarter - 14-0
- 3rd Score - Touchdown - Patrick #DET Lions #Q2#13'#78#15
- 2nd Quarter Race to 6 - #DET Lions #Q2#13'#78#15
- 5th Drive - First Down - Yes #DET Lions #Q2#13'#78#15
- 5th Drive - Offensive Touch Down - #DET Lions #Q2#13'#78#15
- 1 PAT - #DET Lions #Q2#13'#78#15
- 4th Score - Touchdown - Cook #BUF Bills #Q2#8'#412#15
- Race to 20 - #BUF Bills #Q2#8'#412#15
- 6th Drive - First Down - Yes #BUF Bills #Q2#8'#412#15
- 6th Drive - Offensive Touch Down - #BUF Bills #Q2#8'#412#15
- 1 PAT - #BUF Bills #Q2#8'#412#15
- 5th Score - Touchdown - #DET Lions #Q2#2'#727#15
- 2nd Quarter Race to 12 - #DET Lions #Q2#2'#727#15
- 7th Drive - First Down - Yes #DET Lions #Q2#2'#727#15
- 7th Drive - Offensive Touch Down - #DET Lions #Q2#2'#727#15
- 1 PAT - #DET Lions #Q2#2'#727#15
- 8th Drive - First Down - Yes #BUF Bills #Q2#1'#790#15
- 8th Drive - Field Goal Attempt #BUF Bills #Q2#1'#790#15
- 9th Drive - First Down - Yes #DET Lions #Q2#0'#862#15
- 9th Drive - Field Goal Attempt #DET Lions #Q2#0'#862#15
- Score After 2nd Quarter - 21-14
- 6th Score - Touchdown - Cook #BUF Bills #Q3#13'#112#15
- 3rd Quarter Race to 6 - #BUF Bills #Q3#13'#112#15
- Race to 25 - #BUF Bills #Q3#13'#112#15
- 11th Drive - First Down - Yes #BUF Bills #Q3#13'#112#15
- 11th Drive - Offensive Touch Down - #BUF Bills #Q3#13'#112#15
- 1 PAT - #BUF Bills #Q3#13'#112#15
- 12th Drive - First Down - No #DET Lions #Q3#11'#225#15
- 12th Drive - Punt #DET Lions #Q3#11'#225#15
- 13th Drive - First Down - Yes #BUF Bills #Q3#6'#486#15
- 13th Drive - Punt #BUF Bills #Q3#6'#486#15
- 14th Drive - First Down - Yes #DET Lions #Q3#4'#606#15
- 14th Drive - Turnover #DET Lions #Q3#4'#606#15
- 7th Score - Touchdown - Shakir #BUF Bills #Q3#3'#702#15
- 3rd Quarter Race to 12 - #BUF Bills #Q3#3'#702#15
- Race to 30 - #BUF Bills #Q3#3'#702#15
- 15th Drive - First Down - Yes #BUF Bills #Q3#3'#702#15
- 15th Drive - Offensive Touch Down - #BUF Bills #Q3#3'#702#15
- 1 PAT - #BUF Bills #Q3#3'#702#15
- Race to 35 - #BUF Bills #Q3#3'#702#15
- 8th Score - Touchdown - St.Brown #DET Lions #Q3#1'#789#15
- 16th Drive - First Down - Yes #DET Lions #Q3#1'#789#15
- 16th Drive - Offensive Touch Down - #DET Lions #Q3#1'#789#15
- 1 PAT - #DET Lions #Q3#1'#789#15
- Score After 3rd Quarter - 35-21
- 17th Drive - First Down - Yes #BUF Bills #Q4#13'#66#15
- 17th Drive - Field Goal Attempt #BUF Bills #Q4#13'#66#15
- 9th Score - Field Goal - #BUF Bills #Q4#13'#66#15
- 10th Score - Touchdown - Gibbs #DET Lions #Q4#11'#197#15
- 4th Quarter Race to 6 - #DET Lions #Q4#11'#197#15
- 18th Drive - First Down - Yes #DET Lions #Q4#11'#197#15
- 18th Drive - Offensive Touch Down - #DET Lions #Q4#11'#197#15
- 1 PAT - #DET Lions #Q4#11'#197#15
- 11th Score - Touchdown - Davis #BUF Bills #Q4#11'#197#15
- 4th Quarter Race to 9 - #BUF Bills #Q4#11'#197#15
- Race to 40 - #BUF Bills #Q4#11'#197#15
- 19th Drive - First Down - Yes #BUF Bills #Q4#11'#197#15
- 19th Drive - Offensive Touch Down - #BUF Bills #Q4#11'#197#15
- 1 PAT - #BUF Bills #Q4#11'#197#15
- 12th Score - Touchdown - Gibbs #DET Lions #Q4#8'#414#15
- 4th Quarter Race to 12 - #DET Lions #Q4#8'#414#15
- 20th Drive - First Down - Yes #DET Lions #Q4#8'#414#15
- 20th Drive - Offensive Touch Down - #DET Lions #Q4#8'#414#15
- 1 PAT - #DET Lions #Q4#8'#414#15
- 21st Drive - First Down - Yes #BUF Bills #Q4#2'#779#15
- 21st Drive - Field Goal Attempt #BUF Bills #Q4#2'#779#15
- 13th Score - Field Goal - #BUF Bills #Q4#2'#779#15
- 14th Score - Touchdown - Williams #DET Lions #Q4#0'#884#15
- 22nd Drive - First Down - Yes #DET Lions #Q4#0'#884#15
- 22nd Drive - Offensive Touch Down - #DET Lions #Q4#0'#884#15
- 1 PAT - #DET Lions #Q4#0'#884#15