Head to Head
| Mexico Liga MX | 2015/11/07 03:30 | Santos Laguna v Mazatlan FC | W | 2-3 |
| Mexico Liga MX | 2015/04/04 01:30 | Mazatlan FC v Santos Laguna | L | 0-1 |
| Mexico Liga MX | 2014/10/05 01:00 | Santos Laguna v Mazatlan FC | D | 2-2 |
Home History
| Mexico Liga MX | 2016/04/24 02:00 | Dorados v Mazatlan FC | L | 1-0 |
| Mexico Liga MX | 2016/04/17 01:30 | Mazatlan FC v Pachuca | W | 1-0 |
| Mexico Liga MX | 2016/04/10 01:30 | Atlas v Mazatlan FC | W | 1-2 |
| Mexico Liga MX | 2016/04/03 02:30 | Mazatlan FC v Puebla | W | 2-0 |
| Mexico Liga MX | 2016/03/27 02:30 | Mazatlan FC v Jaguares de Chiapas FC | W | 2-0 |
| Mexico Liga MX | 2016/03/21 00:00 | Unam Pumas v Mazatlan FC | L | 4-2 |
| Mexico Liga MX | 2016/03/13 02:30 | Mazatlan FC v Monterrey | L | 1-3 |
| Mexico Cup | 2016/03/10 03:00 | Leon v Mazatlan FC | W | 1-4 |
Away History
| Mexico Liga MX | 2016/04/24 00:00 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexico Liga MX | 2016/04/16 22:00 | Cruz Azul v Santos Laguna | W | 0-1 |
| Mexico Liga MX | 2016/04/09 02:30 | Santos Laguna v Veracruz | W | 2-0 |
| CONCACAF Champions Cup | 2016/04/06 02:00 | Club America v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2016/04/02 02:30 | Toluca v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2016/03/20 03:00 | Dorados v Santos Laguna | L | 3-1 |
| CONCACAF Champions Cup | 2016/03/17 02:00 | Santos Laguna v Club America | D | 0-0 |
| Mexico Liga MX | 2016/03/12 03:30 | Santos Laguna v Pachuca | W | 3-2 |