Head to Head
| Mexico Liga MX | 2015/08/15 02:30 | Santos Laguna v Club America | W | 0-2 |
| Mexico Liga MX | 2015/03/14 23:00 | Club America v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2014/09/27 02:30 | Santos Laguna v Club America | W | 1-4 |
| Mexico Liga MX | 2014/05/04 02:00 | Santos Laguna v Club America | L | 3-1 |
| Mexico Liga MX | 2014/05/01 01:00 | Club America v Santos Laguna | W | 5-3 |
Home History
| Mexico Liga MX | 2016/01/31 03:00 | Dorados v Club America | W | 0-3 |
| Mexico Liga MX | 2016/01/23 23:00 | Club America v Pachuca | L | 1-4 |
| Mexico Liga MX | 2016/01/17 02:30 | Atlas v Club America | W | 0-3 |
| Mexico Liga MX | 2016/01/09 23:00 | Club America v Puebla | D | 0-0 |
| FIFA Club World Cup | 2015/12/16 07:30 | Club America v TP Mazembe | W | 2-1 |
| FIFA Club World Cup | 2015/12/13 07:00 | Club America v Guangzhou FC | L | 1-2 |
| Mexico Liga MX | 2015/12/06 18:00 | Unam Pumas v Club America | W | 1-3 |
| Mexico Liga MX | 2015/12/04 01:00 | Club America v Unam Pumas | L | 0-3 |
Away History
| Mexico Liga MX | 2016/01/30 03:30 | Santos Laguna v Queretaro | W | 2-0 |
| Mexico Liga MX | 2016/01/23 03:30 | Tijuana v Santos Laguna | W | 1-3 |
| Mexico Liga MX | 2016/01/16 03:30 | Santos Laguna v Chiapas | W | 1-0 |
| Mexico Liga MX | 2016/01/10 02:06 | Leon v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2015/11/22 23:00 | Chivas Guadalajara v Santos Laguna | W | 0-3 |
| Mexico Liga MX | 2015/11/07 03:30 | Santos Laguna v Mazatlan FC | L | 2-3 |
| Mexico Liga MX | 2015/11/01 01:00 | Tigres UANL v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2015/10/24 02:30 | Santos Laguna v Cruz Azul | L | 1-2 |